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Synapse

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Synapse
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Synapse

Structure connecting neurons in the nervous system

In the nervous system, a synapse is a structure that allows a neuron to exchange (receive or send) signals with another cell in its immediate vicinity. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are known to produce synchronous network activity in the brain, but can also result in complicated, chaotic network level dynamics. Therefore, signal directionality cannot always be defined across electrical synapses. Synapses are essential for the transmission of neuronal impulses from one neuron to the next, playing a key role in enabling rapid and direct communication by creating circuits. In addition, a synapse serves as a junction where both the transmission and processing of information occur, making it a vital means of communication between neurons. At the synapse, the plasma membrane of the signal-passing neuron (the presynaptic neuron) comes into close apposition with the membrane of the target (postsynaptic) cell.

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Article table of contents 19 sections
1 Definition
2 History
3 Types
3.1 Excitatory and inhibitory
3.2 Interfaces
4 Conversion of chemical into electrical signals
5 Release of neurotransmitters
6 Synaptic polarization
7 Presynaptic modulation
8 Effects of drugs on ligand-gated ion channels
9 Biogenesis
10 Role in memory
10.1 Potentiation and depression
10.2 Mechanism of protein kinase
11 Experimental models
12 Synapses and diseases
13 Additional images
14 See also
15 References
Categories
Neural synapseSignal transduction
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Wikidata knowledge graph Q187181

synapse

junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell

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Instance of
cellular component
Subclass of
cell junction
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