"If nothing changes, all remaining Nitter instances will go down eventually"
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Show HN: I'm 13 and built an AI that remembers context across conversations
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Nike.com's robots.txt
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Brad Pitt’s housing dream for Hurricane Katrina survivors turned into nightmare
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Nikki Haley: "I want everybody's name" (on social media)
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Show HN: I made NIGHT.FM, a cyberpunk-inspired online radio
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Lil Wayne - LEGACY III - 55 Minutes Best of Lil Wayne Music (ft. Migos, 2 Chainz, Tyga, Ni…
New mixtape of Lil Wayne - LEGACY III - 55 Minutes Best of Lil Wayne Music (ft. 2 Chainz, Migos, Tyga, Nicki Minaj).More videos and subscribe here: / @L...
Neural control of the lower urinary tract
This article summarizes anatomical, neurophysiological, pharmacological, and brain imaging studies in humans and animals that have provided insights into the neural circuitry and neurotransmitter mechanisms controlling the lower urinary tract. The functions of the lower urinary t…
Learned control of urinary reflexes in cattle to help reduce greenhouse gas emissions
Indiscriminate voiding of excreta by cattle contributes to greenhouse gas (GHG) emissions and soil and water contamination<sup>1</sup><sup>,</sup><sup>2</sup>. Emissions are higher in animal-friendly husbandry offering cattle more space<sup>2</sup> - a trade-off we call the 'clim…
Urinary incontinence during sexual intercourse: a common, but rarely volunteered, symptom
A total of 400 women referred consecutively to a gynaecological urology clinic was questioned with regard to their sexual activity and were subsequently investigated by cystometry to establish the prevalence of urinary incontinence occurring during intercourse, and to define the…
Sex and Gender Differences in the Pharmacology of the Overactive Urinary Bladder
Dysfunction of the lower urinary tract in general and the overactive bladder syndrome (OAB) in particular are prevalent and have major impact on the quality of life of the afflicted patients and their partners. We concisely review sex and gender differences in patients and animal…
Amniotic fluid: not just fetal urine anymore
Amniotic fluid (AF) is a complex substance essential to fetal well-being. This article reviews recent discoveries and the current understanding of the origin and circulation of AF and its nutritive, protective, and diagnostic functions. Future directions for AF research are also…
Is seated voiding associated with lower urinary tract symptoms, health conditions, or mari…
Approximately 60% of Japanese men void in the sitting position at home. There are certain differences in the associations of LUTS and health conditions with voiding position by age, while seated voiding is consistently associated with marital status throughout all ages, which imp…
Urinating standing versus sitting: position is of influence in men with prostate enlargeme…
For healthy men, no difference is found in any of the urodynamic parameters. In patients with LUTS, the sitting position is linked with an improved urodynamic profile.
Cerebral mechanisms and voiding function
Some of the most recent work investigating the cerebral mechanisms involved in bladder control has been very helpful in adding to our understanding of bladder dysfunction. The group behind this work, from London, presents a mini-review which will help to update our knowledge in t…
Urethral afferent nerve activity affects the micturition reflex; implication for the relat…
These results indicate that in the anesthetized rat activation of urethral afferents by urethral perfusion can modulate the micturition reflex. Thus in patients with stress urinary incontinence, leakage of urine into the proximal urethra may stimulate urethral afferents and facil…
Ultrastructural evidence for direct projections from the pontine micturition center to gly…
During micturition, according to the concept of Blok, Holstege, and colleagues ([1997] Neurosci. Lett. 233:109-112), the pontine micturition center (PMC) elicits bladder contraction by way of direct excitation of the parasympathetic bladder motoneurons. At the same time, the PMC…
Direct projections from the periaqueductal gray to the pontine micturition center (M-regio…
Micturition is a spino-bulbo-spinal reflex. The bulbospinal part of this reflex is formed by the projections from the M-region, also called the pontine micturition center or Barrington's nucleus, to the preganglionic parasympathetic motoneurons in the sacral cord innervating the…
Reflexes to sacral parasympathetic neurones concerned with micturition in the cat
1. Reflexes to sacral parasympathetic neurones were studied by electrophysiological techniques in decerebrate, in chloralose-anaesthetized, and in chronic spinal cats.2. Excitatory reflexes from pelvic nerve and sacral somatic afferent nerve fibres were present before and after c…
Neurophysiology of lower urinary tract function and dysfunction
With the continued aging of the population, the incidence of conditions associated with bladder control will continue to grow. In this article, we review the neurophysiology and pathophysiology of the bladder and urethra and discuss logical concepts for the development of novel d…